Hua: 2-phenylacetamide
tātai rāpoi: C8H9NO
Te taumaha ngota: 135.17
Ingoa Ingarihi: Phenylacetamide
Ko te ahua: He tawerewere ma, he kiripiri ahua rau ranei.Mp 157-158 ℃, bp 280-290 ℃ (decomposition).Wairewa i roto i te wai wera me te waiwaro, paku wairewa ki te wai matao, ether, me te benzene.
Whakamahinga: Takawaenga o nga raau taero penei i te penicillin me te phenobarbital.Ka whakamahia hoki mo te whakarite i te waikawa phenylacetic, nga mea kakara, me nga pesticides.
Tikanga 1) Masuko F，Katsura T.US 4536599A1.1985.
Tāpirihia te 117.2 g (1.0 mol) o te phenylacetonitrile (2), 56.1 g o te 25% te wairewa pāhare pāhare pāporo, 291.5 g o te 35% hydrogen peroxide wairewa wai, 1.78 g o te benzyltriethylammonium chloride, me te 351.5 g o te tauhohenga flaskpanol.Oho me te tauhohe i te 50 ℃ mo te 4 haora.I muri i te otinga o te tauhohenga, ka whakaetohia te isopropanol i raro i te pehanga iti, ka whakamatao, ka tātarihia, ka horoia ki te wai, ka whakamaroke kia whiwhi pūhui (1) 128.5 g, mp 155 ℃, me te 95%.
Tikanga 2) Furniss BS，Hannaford AJ，Rogers V，et al.Vogel's Textbook of Practical Chemistry.Longman London and New York.Putanga tuawha，1978：518.
Tāpirihia te 100 g (0.85 mol) o te phenylacetonitrile (2) me te 400 mL o te waikawa pūhaumāota ki te ipu tauhohenga.I raro i te whakakorikori, tauhohe i te 40 ℃ mo te 40 meneti, ka hiki te pāmahana ki te 50 ℃.Haere tonu ki te urupare mo te 30 meneti.Matao ki te 15 ℃ ka tāpirihia te 400 mL o te wai māturu matao kia maturuturu.Te whakamatao i roto i te kaukau wai tio, ka tātari i nga tioata.Tāpirihia te totoka ki te 50 mL o te wai ka tino whakaoho kia tangohia te waikawa phenylacetic.Tātarihia ka maroke i te 50-80 ℃ kia whiwhi 95 g o te phenylacetamide (1), mp 154-155 ℃, me te hua o te 82%.Te whakamahana me te waihano, mp 156 ℃.
Wā tuku: Apr-11-2023